Welcome back to the Top 12 Running Back Plays for Week 10! We had only 4 running backs rush for over 100 yards in Week 9, and those 4 running backs will be listed below. The only other player to surpass the 100-yard rushing mark was Baltimore Ravens’ quarterback Lamar Jackson. We also witnessed a couple of returns, as David Montgomery and Christian McCaffrey both returned from injury. This was also the first week without the Titans’ star running back Derrick Henry. Let’s take a look at some of the players that could help replace Henry in your lineups.
Top 12 Running Back Plays for Week 10
Jonathan Taylor vs JAX

Jonathan Taylor will be the first running back we address in Week 10. Taylor and the next running back could be seen as 1a and 1b in my opinion. Taylor will get the nod this week due to his matchup against the Jacksonville Jaguars. Taylor ran for 172 yards and 2 touchdowns last week versus the New York Jets. Taylor has rushed for 821 yards and 8 touchdowns through 9 weeks. The Jacksonville defense has allowed 821 rushing yards and 10 touchdowns.
Nick Chubb at NE
Nick Chubb could be considered the top running back this week, but I just have him a spot lower since the Browns will be headed to New England in Week 10. Nick Chubb is coming off a game where he rushed for 137 yards and 2 scores against the Cincinnati Bengals. Chubb missed 2 games this season because of an injury, however, he still rushed 721 yards and 6 touchdowns in those 7 games. New England’s defense has given up 980 yards rushing but only 5 touchdowns to opponents this season.
Najee Harris vs DET
Najee Harris has scored at least 1 touchdown either rushing or receiving in each of the last 5 games. Harris has rushed for 451 yards and 4 touchdowns through the first 8 weeks of the season while adding 40 receptions for 289 yards and 2 scores. In Week 10, the Steelers will host the winless Detroit Lions. The Lions have given up 1,076 yards and 10 touchdowns to opponents through 9 games. Even though Harris might not have a high rushing total so far this season, his usage in the receiving game will help your lineup in PPR leagues.
Austin Ekeler vs MIN
Austin Ekeler has rushed for just 479 yards and 5 touchdowns, and he has also added 36 receptions for 325 yards and 3 scores. He has only one game this season where he rushed for more than 66 yards, he ran for 117 yards against the Raiders in Week 4. The Vikings have given up the sixth-most rushing yards with 1,093 and 7 touchdowns this season. Minnesota is the team that allowed Lamar Jackson to rush for 120 yards against them in Week 9. Ekeler’s usage in the passing game along with his rushing game could make him one of the top running back plays this week.
Christian McCaffrey at ARI

Christian McCaffrey played only 49% of the Panthers’ offensive snaps in Week 9 against the Patriots. He was still able to manage to have 52 yards rushing to go along with his 4 receptions for 54 yards. McCaffrey was out since he was injured against the Houston Texans in Week 3. McCaffrey has 253 yards and a touchdown to go with 20 catches for 217 yards in 3 games. The Panthers will head to Arizona in Week 10. The Cardinals have given up 1,000 yards and 4 touchdowns to opponents this season.
Javonte Williams vs PHI
Denver Broncos rookie running back Javonte Williams ran for 111 rushing yards against the Dallas Cowboys in Week 9. That was his highest total of the season, as his next highest total was 64 yards in Week 2 against Jacksonville. The Broncos have been in a timeshare at running back for most of the season, and Williams made the most of his opportunity last week. In Week 10, the Broncos will face the Philadelphia Eagles. The Eagles have given up 1,077 yards and 10 scores on the ground through 9 games.
Zach Moss vs NYJ
Zach Moss has only 65 rushing attempts for 233 yards and 3 scores this season, and he also has 18 receptions for 166 yards and 1 touchdown in the passing game. Buffalo did not have a good game against Jacksonville in Week 9. Moss had only 3 attempts for 6 yards. The Bills will look to rebound against the New York Jets in Week 10. The Jets have allowed opponents to rush for 1,066 yards and 15 touchdowns, and the 15 touchdowns are tied for the most in the NFL.
Ezekiel Elliott vs ATL
Ezekiel Elliott has rushed for 100 yards only twice this season. Through the first 8 weeks, Elliott has 622 yards and 5 scores on the ground and 23 receptions for 153 yards and 1 touchdown. Zeke is coming off his lowest snap count of the season so far against the Broncos at 53%. The game was out of hand, and they didn’t need to risk Zeke getting hurt. The Atlanta Falcons will be coming to town in Week 10. The Falcons have given up 985 yards and 7 scores this season.
D’Andre Swift at PIT

D’Andre Swift has rushed for only 289 yards and 3 scores this season on 90 attempts. Swift, however, benefits from being used in the passing game by catching 47 passes for 415 yards and 2 scores. Swift has played 71% or more of the Lions’ offensive snaps over the last 5 games. He can attribute his low rushing totals due to the Lions trailing in a lot of games this season. In Week 10, the Lions will host the Pittsburgh Steelers. The Steelers have one of the better run defenses in the NFL, allowing 878 yards and 4 touchdowns. Swift should see a heavy amount of targets in the passing game.
Leonard Fournette vs WAS
Leonard Fournette and the Tampa Bay Buccaneers are coming off of a bye in Week 9 and will host the Washington Football Team in Week 10. Leonard Fournette has 439 yards and 4 scores on the ground and has caught 30 receptions for 239 yards. Washington’s run defense has given up only 821 yards and 7 scores this season. However, Tom Brady likes to use Fournette as a receiving option if he feels like his receivers aren’t open downfield.
Aaron Jones vs SEA (SNF)
Aaron Jones has more receiving touchdowns (4) than rushing touchdowns (3) through 9 weeks. He also has 516 yards rushing and has caught 33 passes for 237 yards. Aaron Rodgers missed the Packers’ Week 9 game against the Chiefs, but he could be back for the Week 10 matchup against the Seattle Seahawks. Aaron Jones has caught at least 2 passes a game with Rodgers under center. The Seahawks have allowed 1,021 yards and 6 scores on the ground this season.
Dalvin Cook at LAC
Dalvin Cook will come with a disclaimer. There have been reports that were released on Tuesday night and Wednesday morning that could affect his playing time. If Cook doesn’t play, his backup Alexander Mattison would fit in as the last spot on this list. The Vikings like to dump off passes to the running back, and the running backs have a combined 5 games over 100 yards rushing as well. The Vikings will head to LA to face the Chargers on Sunday. The Chargers have allowed a league-leading 1,293 rushing yards and 11 touchdowns.
That wraps up the Top 12 Running Back Plays for Week 10. As always thank you for stopping by. Remember, to check out articles like this and more, go to RotoHeat.com, and join the conversation in our Facebook group.